New technology for the synthesis and manufacturing of biomimetic implants derived from biogenic resources used for bone reconstruction surgery

This project aims the development and implementation of a new complex and reproducible synthesis technology of biomimetic ceramic materials derived from marble and seashell precursors and their performance assessment as potential use in restorative and reconstructive surgery.

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GENERAL OBJECTIVE

This project aims the development and implementation of a new complex and reproducible synthesis technology of biomimetic ceramic materials
derived from marble and seashell precursors and their performance assessment as potential use in restorative and reconstructive surgery.


OBJECTIVE 2017

Concept design and experimental route for the synthesis of hydroxyapatite powder from marble and seashells precursor`s type. Synthesis of 3D structures with tunable structural characteristics and porosity

OBJECTIVE 2018

In vitro evaluation of the biomimetic 3D structuresSelection of the optimal synthesis route and advantageous materials used in bone regeneration applications. Development of a laboratory work precedure for the manufacturing of experimental models.

  • Requirements

    Use of strictly biogenic materials.

  • Analysis Methods

    Morphology, particle size and chemical composition by SEM/EDS and TEM, structure by XRD and FT-IR and mass stability by TGA-DSC analysis.

  • Primary goal

    Obtain an original reproducible technology for the synthesis and processing of biogenic hydroxyapatite

  • Analysis

    Testing the apatite formation in vitro is imperative for the assessment of cell adhesion, inflammatory responses and for subsequent in vivo testing

Estimated results

A synthesis technology of biomimetic ceramic materials derived from marble and seashell.